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The 10 Best Poison Ivy Killer Brands

Getting rid of poison ivy can be tough.

You need to kill it roots and all if you don’t want it growing back.

But removing it by hand is tricky because of its toxic leaves that cause a severe reaction on your skin.

It’s a lot easier when you use the best poison ivy killer.

Our recommended product is Spectracide Weed And Grass Killer. This powerful herbicide quickly kills poison ivy and any other unwanted plants you apply it to.

Our top choices at a glance:

All links lead to Amazon, where you can find more information & customer reviews.

The Best Poison Ivy Killer Reviews

Spectracide Weed And Grass Killer Concentrate

Spectracide Weed And Grass Killer Concentrate will take care of poison ivy as well as any other weeds and brush in your yard. Including dandelions, plantain, wild violets, clover, crabgrass, and chickweed.

The bottle of concentrate contains the active ingredients diquat dibromide, fluazifop-p-butyl, and dicamba. You can use it with a hose-end sprayer if you need to treat a large area. Or mix it with water in a tank sprayer.

It’s rainproof in 15 minutes. So you don’t have to worry about showers or watering washing away its effectiveness. But for best results, it’s recommended to use when its sunny and temperatures are greater than 60 °F.

The fast-acting formula sees weeds wilting and shriveling within a day. With many of them looking dead after 2-3 days. But many customers find that results are not visible quite as fast as the 3 hours that’s claimed, which is a small complaint. Occasionally, tough plants may require more than one application.

It’s easy to use on areas where you don’t have existing plants you want to keep, and are just looking to kill the weeds, vines, brush, and brambles infesting the area.

But more care needs to be taken when spraying around flower beds and near your lawn, because it will kill flowers and grass as well.

  • Powerful
  • Kills all unwanted weeds including poison ivy
  • Fast results compared to many other products
  • Rainproof after just 15 minutes
  • Strong enough for commercial use
  • Doesn’t always kill as quickly as the 3 hours advertised
  • Non-selective—so be careful using it around plants and grass that you want to keep

RoundUp Poison Ivy Plus Tough Brush Killer

This Roundup product is a 2-in-1 brush killer that also works to eliminate poison ivy. Other common invasive shrubs it’s effective against include wild blackberry, kudzu, poison oak, and poison sumac.

It’s available as a ready to use product with either a wand or a trigger for application. And you can also get it in concentrate form to mix with water in a sprayer, which is very economical when treating large yards.

RoundUp is completely rainproof within half an hour of application. With results visible within 24 hours. The powerful formula penetrates the wax-like texture of the leaves and stems of invasive plants. Killing all the way to the roots.

For best results, we recommend using this product in a well-ventilated area. Apply to healthy, growing poison ivy and other invasive plants when the wind has died down so there is no spread to desirable plants in your garden.

  • Good for use in wooded lots and brush-invaded yards
  • Prevents regrowth of poison ivy and other plants
  • Also effective at killing stumps
  • Stores well unopened for up to 48 months
  • The wand sometimes breaks on the ready to use version—but the concentrate is easy to use with any sprayer

Ortho MAX Poison Ivy And Tough Brush Killer

Formulated for poison ivy, tough brush, and weeds, this popular offering in the Ortho MAX weed killer line contains Triclopyr 8% as a primary ingredient. It’s effective at killing over 60 types of stubborn plants including kudzu, poison oak, and wild blackberry.

The 32-oz. bottle of poison ivy killer concentrate goes a long way. Making approximately 8 gallons of solution when diluted. And delivering a cost-effective treatment option for infested areas of your yard.

Rainproof within just a couple of hours of applying, you often need two applications to complete the job. With a complete kill taking between 2-6 weeks. You may notice within a few days that some of the invasive plants you treated are starting to turn brown or yellow.

Dilution depends on your method of application. For best results, connect the bottle of concentrate to an Ortho Dial And Spray hose-end sprayer, or any brand of tank sprayer.

  • Value for money
  • Also effective at killing woody plants, stumps, vines, honeysuckle, ragweed, and more
  • You can wash it off if accidentally used on desirable plants (within 2 hours of application)
  • Can be slow to work at the recommended dilution

Brushtox Brush Killer Concentrate


A powerful formula that efficiently kills poison ivy, Brushtox Brush Killer Concentrate also controls woody plant growth such as mesquite, wild rose, and sweetgum. As well as broadleaf weeds like Canada thistle and dog fennel.

The concentrated herbicide can treat up to an acre of land per 32 oz. bottle. And can be used on ornamental turf, ditch banks, grass pastures, and fencerows.

As it’s so toxic, it’s recommended to wear protective clothing when using it. And be careful where you spray, because anything you use it on probably won’t be growing back.

It’s best to use Brushtox Brush Killer Concentrate in dry spells to avoid run-off into groundwater or soil. Although the product is rain-proof within 2 hours.

  • Great value for money per acre treated
  • Typically only needs one application
  • Very powerful formula containing 61% Triclopyr
  • Very toxic—so use protective clothing

Southern CROSSBOW Weed & Brush Killer

Southern Crossbow

This powerful herbicide is one of the best weed and brush killers.

It combines Triclopyr, 2-D, and 4-D in an effective formula for killing most woody brush, trees, and broadleaf weeds, including poison ivy.

It works by halting plant growth almost immediately. And on plants such as clover and dandelions, it can kill them overnight. But you may have to wait 3-6 days for the treated poison ivy plant to start shriveling and turning brown or yellow. Followed by death after 2-3 weeks.

As with most herbicides, it works best when undesirable plants are putting out new, vulnerable growth. When treating more mature plants, a second treatment is recommended to kill them off completely.

It’s rain-proof within two hours of application.

  • Effective on a wide range of broadleaf weeds, vines, and brush
  • Selective weed killer—so it won’t harm your grass when you follow the instructions
  • Sometimes requires 2 applications to stop weeds returning

BioAdvanced Brush Killer Plus


Previously sold as Bayer Advanced Brush Killer Plus, this BioAdvanced product contains Triclopyr and triethylamine salt as its main active ingredients.

It’s formulated to kill over 70 invasive shrubs, brush, and weeds. Including kudzu, poison oak, and poison ivy. As well as the most common broadleaf weeds and many bushy plants.

It’s also great for thorny and tough weeds, such as bramble bushes, that can be uncomfortable to clear away by hand.

This product can be used anywhere you have poison ivy or tough brush that needs to go. Along fence lines and around buildings, walkways, trails, and cabins. The BioAdvanced special penetrating formula enters target plants through leaves and roots and is translocated around the plant to kill it from within.

If you accidentally get it on plants you want to keep then you can wash them quickly to prevent harm. But it’s best to avoid using this product on windy days as the drift could damage your garden and may be harmful to pets or children in the immediate area.

Apply to fully-leafed growth or actively growing invasive plants. This herbicide is rain-proof within 4 hours of application, and treats up to 4,000 sq. ft.

  • Fast acting on poison ivy
  • Systemic weed killer that kills plants to the root
  • Works well for tough brush and brambles
  • It can take over a month to see significant results with some plants

Bonide BND506 Poison Oak & Ivy Killer


Bonide BND506 Poison Oak And Ivy Killer is a selective weed killer that won’t damage the grass on your lawn. But it will take care of most broadleaf weeds, including clover, dandelion, creeping charlie, thistle, and stinging nettle.

It kills unwanted plants to the roots. With effects noticeable within a few days. Although it can take up to 4 weeks for complete results on poison ivy.

Bright greenish-blue in color and pungent-smelling, this herbicide contains a 2-D and 4-d combination, along with dimethylamine, to give proven results. It arrives ready to use with no diluting required. And the spray nozzle makes it ideal for spot treatment.

  • Kills broadleaf weeds
  • Starts working overnight
  • Doesn’t harm lawn grass
  • Kills poison ivy to the root
  • Ready-to-use—no mixing
  • Best poison oak killer
  • It can take up to 4 weeks to completely kill some plants

Ferti-lome Brush & Stump Killer


Ferti-lome Brush & Stump Killer is effective at eliminating poison ivy. But you have to be careful when using it, because it will also kill your grass. Cut the poison ivy down to a few inches, and then use a paper towel wrapped around what’s left to soak up any excess weed killer while you drench them.

You can also use it to control any unwanted vines, woody plants, strawberry crawlers, blackberry bramble, stumps, thorn bushes, and even invasive cactus.

The main active ingredient is Triclopyr. An ingredient best used in non-crop areas. You can use this product diluted (on leafy plants) and undiluted (on stumps). Use a piece of cardboard to shield good plants while spraying anything unwanted.

The packaging has been re-designed to include a handy brush on the inside of the lid, making this truly a ready-to-use product. Some handy hints in using this product include using an axe to increase the surface area sprayed, and waiting a couple of weeks to let the formula get to work on your stumps before inspecting treatment progress.

  • Fast acting
  • One application is usually enough
  • Kills anything you want to get rid of
  • Because it kills everything you have to be careful when using it

Green Gobbler Natural & Organic Weed & Grass Killer

Green Gobbler Natural & Organic Weed & Grass Killer is a fast-acting organic weed killer. It consists of a 20% corn-derived vinegar that’s 4 times stronger than table vinegar.

Certified for organic use, this product makes quick work of poison ivy, dandelions, clover, chickweed, thistle, and other broadleaf weeds. Its effects are visible within hours, compared to chemical weed killers that often take from days to weeks to show significant results.

But it’s non-selective—so it will kill anything you spray it on. This includes your lawn and flowers, so using cardboard to protect desirable plants is again recommended here.

Because it’s a contact weed killer, it won’t kill the plant to the roots. Instead, it will disintegrate the areas it comes into contact with. So the poison ivy will grow back if you don’t remove the roots by hand.

It’s safe for use around pets and humans, as it’s non-toxic and quickly dries. But you should spray it with care as it can burn.

This organic weed killer is ready-to-use in any location, including residential and agricultural areas. 1-gallon effective covers 1,200 sq. ft.

The company offers a 30 day money back guarantee in support of this product.

  • Fast acting
  • Natural and organic poison ivy killer
  • Non toxic and pet safe
  • Non-selective—so be careful where you spray it
  • Strong acid can burn if you get it on your skin

Pulverize Brush & Vine Killer Spray

Pulverize poison ivy and vine killer comes ready to use in a handheld trigger spray bottle and is a good choice for small jobs and occasional spot treatment.

It contains the active ingredients maleic hydrazide and ammoniated soap of fatty acids. When the solution is directed at the roots of unwanted plants it can kill and prevent the regrowth of many varieties of weeds, vines, and brush. Including poison ivy and poison oak.

It’s good to use on hard surfaces, around containers, planters, sidewalks, buildings, and raised beds, as it’s non-staining. But be careful when using it near lawns as it will also harm the grass.

Results are seen quickly, within hours of thoroughly spraying the target plants.

It comes in a 32 oz. bottle at an affordable price.

  • Ready to use poison ivy killer spray
  • Kills weeds and prevents regrowth
  • Economical
  • It kills grass and other desirable garden plants as well
  • Less suitable for treating larger areas

Buyer’s Guide: Choosing The Best Poison Ivy Killer

poison ivy plant

There are many different products available on the market that can kill poison ivy.

Some of them are formulated specifically for poison ivy and others have a more general formula that kills it along with many other weeds and grasses.

To help you make a decision about which product is right for your situation we’ve prepared this buying guide that covers the main things to consider.

Let’s dive in.

The Type

Poison ivy killers come in 2 different types, natural and chemical:

Natural Poison Ivy Killer

Many of us prefer the idea of using natural and organic methods of weed removal where possible. And you can get rid of poison ivy without using a chemical herbicide. But, it will take time and effort.

Organic herbicides usually contain concentrated vinegar. Because acetic acid is very corrosive, it can kill the parts of the plant that you spray it on. But, for complete removal of poison ivy, the roots will have to be removed, which will require effort to dig or pull them out.

The problem with this is that even when you’re being careful you can still miss parts of the plant which are underground. And if any of it remains, you may find the poison ivy growing back again.

This is why many people think that the best weed killer for ivy is a chemical weed killer instead of applying an organic herbicide.

Chemical Poison Ivy Killer

Chemical weed killers are popular because they deliver effective long-term results when used correctly. And with far less effort than natural methods.

The chemicals in most poison ivy killers are considered toxic, so be careful how you use them. We recommend wearing protective clothing and gloves when handling chemical-based weed killers, and to wash contaminated clothing separately.

It should be noted that most of the active ingredients in the best poison ivy killers contain either glyphosate, triclopyr, or 2 4-D.

Glyphosate is a non-selective herbicide that kills most plants it comes into contact with. It’s most effective for treating broadleaf plants and grasses, killing them to the root.

Triclopyr is a selective man-made herbicide that won’t harm grass. Triclopyr kills broadleaf and woody plants by working systemically from leaf to roots.

2 4-D won’t harm most types of grass and is specially formulated to kill stubborn broadleaf plants like poison ivy. This ingredient causes plant cells to divide and grow continuously, effectively halting normal growth.

Selective Vs Non-selective

Some weed killers target a specific range of plants, such as broadleaf weeds. These are known as selective weed killers and won’t kill your grass and other desirable plants. This is the type to choose if you’re worried about collateral damage as you spray the poison ivy.

Non-selective weed killers will kill everything they come into contact with. They’re great for clearing large areas of many different weeds, brush, and unwanted grasses. But you have to be very careful when using them on your lawn or around flowerbeds or ornamental gardens.

Ease of Use

Some herbicides come ready to spray, which makes them quick and easy to use. They are a good choice for occasional small jobs as you don’t have to mess around with mixing or pouring it into a sprayer.

For larger jobs, it can sometimes be more economical to get a concentrate. Mix it with water in a backpack sprayer to use it. Or attach the bottle to a hose spray nozzle where recommended. This can help you to cover large areas of ground quickly and easily.


Poison ivy is a tenacious, stubborn species. As are many of the plants listed on the labels of herbicides. It’s not uncommon to have to treat an area twice to complete the job.

The best poison ivy killers on the market are not cheap, but they can save you money in the long run. Because many of the cheaper options often require multiple applications, if they manage to complete the job successfully at all.

How to Use Poison Ivy Killer

Although each brand differs in the instructions for use, there are some best practices that are worth being aware of.

Some herbicides are available as ready-to-use products that require very little effort. And others may need mixing and agitating before use. Always follow the directions on the package you are working with to calculate the desired strength you need for the job at hand.

Controlling the application of the best herbicide for poison ivy is easiest when using a sprayer wand. It gives you more control than a normal spray bottle. And allows you to get through the growth in front of you and right down to the base (near the roots, new leaves, and vulnerable growth) of poison ivy and other unwanted plants.

For best results, saturate the leaves of poison ivy plants. Take care to avoid rain, windy days, and using near humans, animals, or water. If possible, use a sheet of cardboard to avoid drift or accidentally spraying other plants. And wear protection if necessary.

If you can, pick a time when there’s no rain forecast for the day. Although most products claim to be rainproof within a certain number of hours, the longer the chemicals stay on the leaves without exposure to water the more likely they are to be absorbed rather than washed off.

The best time to apply herbicides to poison ivy is usually late spring or early summer when the plant is actively growing.

For stubborn growths, you may need to re-apply the herbicide for a complete kill. But be aware that some poison ivy killers can take up to a month to do the job.


Poison ivy can be difficult to remove by hand. If you don’t get rid of it completely, roots and all, it will grow back. And it causes an itchy reaction on your skin if you touch it.

But purchasing the right product makes killing poison ivy a lot easier.

So, what is the best poison ivy killer on the market?

Our best rated product is Spectracide Weed And Grass Killer. This fast-acting weed killer will kill poison ivy to the root. And can be used on a wide range of broadleaf weeds, vines, and brush, taking care of any weed infestations you have in the future.

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